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Please see the other data files contained in the \"KIT Daphnia data on nano particles\" dataset.\n\n\"original_daphnia\" data  is compiled from research articles in which nanotoxicity toward Daphnia Magna was measured according to the test guidelines from OECD and US EPA. Toxic response caused by nanomaterials have been assayed; however, the assay outcomes were varied between research articles. Therefore, this data set was compiled for meta-analysis to figure out what may be the cause of data heterogeneity between diverse assay outcomes.\n\nThis data set contains physicochemical properties of nanomaterials, experimental conditions for assays and toxic response measurement.\n\nNotes: 1) Most of physicochemical properties of nanomaterials were taken from the research articles without considering measurement details for them since measurement details were often absent in the articles. Therefore, further details only could be found in reference research article. 2) Since nanomaterials were easily aggregated in media, dispersion methods were applied to make nanomaterials being nano-sized particle. Centrifuge, stir, sonication, and filter were four dispersion methods used among research articles.\n\nAmong collected publications, research articles that didn’t match the internal criteria were removed: (1) assay was not experimented according to OECD or US EPA TGs, (2) toxic response in the control media was higher than 20%, (3) toxic response in the control media was not given, (4) the number of D.Magna was not given, (5) different daphnia species were used in the assay, (6) coating material or chemicals treated with NPs caused toxic response by themselves without NPs, (7) descriptors for NPs were not provided, (8) The media treated with NPs contained more than two species including D. Magna except algae, which is food for D.Magna, (9) phototoxicity assay results, (10) multigeneration assay results and (11) bioaccumulation or uptake assay results. It was assumed that experimental errors between assay results could be minimized by following protocols of OECD or US EPA test guidelines (TGs) (Standard 1). OECD and US EPA TGs mentioned that toxic responses in the control media shouldn’t exceed 20%; therefore, the data in which the control data was not given or toxic responses were higher than 20% in the control media were considered unreliable and so removed (Standard 2 and 3). Each toxicity assays were conducted with different number of organisms. Even though concentration of NPs applied in the test media was equal, each D.Magna could be exposed to different concentration of NPs if the number of organisms in the test tube was different from one another; hence, literatures that mentioned the exact number of D.Magna in each test tube were collected (Standard 4). Due to the fact that we used broad terms for searching, some of literatures studied with different daphnia species. Such data was also removed because use of different species could contribute to increase of noise in data (Standard 5). Current study aimed to study toxic responses of NPs thus the data in which coating materials or co-treated compounds in the media caused toxic response by themselves without NPs were removed (Standard 6). In few research articles, TEM diameters on NPs were not provided. Since we can’t be sure whether the experiments truly used NPs, data were removed (Standard 7). Concentration of NPs exposed to organisms could be influenced by the number of species in the media; hence, data experimented with more than two species including D.Magna were removed. However, algae was exception since it was food for D.Magna (Standard 8). Phototoxicity assays were focused on TiO2 NPs alone; hence, it was impossible to assess phototoxicity of NPs with diverse core materials (Standard 9). Multigeneration assays aimed to check toxic response in offspring bred from an organism exposed to NPs. Such data were removed as toxic responses were measured from D.Magna that was not directly exposed to NPs (Standard 10). Bioaccumulation or uptake assays were mainly conducted to check amount of NPs accumulated in an organism. It is related with toxic responses; however, it is not exactly toxic responses (Standard 11).\n\nCitation: \"Meta-analysis of Daphnia magna nanotoxicity experiments in accordance with test guidelines\", Shin, Hyun Kil & Seo, Myungwon & Shin, Seong & Kim, Kwang-Yon & Park, June-Woo & No, Kyoung Tai. (2018).\n\nAuthor information: Hyun Kil Shin (Department of predictive toxicology, Korea Institute of Toxicology)\n\nLicence: Attribution CC BY 4.0\n\n","metadata":{"Assay":{"Species":"Daphnia"},"Citations":{"Issue":5,"Journal Name":"Environmental science. Nano.","Volume":3,"Year":2018},"NP type":{"BiMe":"Ag-Au","Me":["Ag","Au","Cu"],"MeOx":["Al2O3","CeO2","Cr2O3","CuO","Fe2O3","Fe3O4","La2O3","NiO","SiO2","TiO2","ZnO"],"carbon":["C60","C70","SWCNT","MWCNT","carbon black","diamond","fullerene","graphene"],"metal":["Ag","Al","Au","B","Cu","Ni","Pd"]},"Original Filename":"original_daphnia.csv"},"isPublic":true}